VISION SYSTEM FOR QUALITY INSPECTION

Harleblister. Accuracy is performance

Harleblister is the colour vision system for quality inspection, designed to check solid dose products during the packaging process on blister thermoformers.

The system performs different controls on the pharmaceutical products, with the aim to grant the best quality of each blister produced on the machine.

Zero-defect production

Optimal controls over any product and material

Perfect machine integration

Real-time inspection results and rejection management

Wizard for working format creation

RELIABLE AND FUTURE PROOF

A PC-based vision inspection system created to stand out

With powerful proprietary algorithms designed to evolve over time, Harleblister is still today the world-class vision system for blister quality inspection, applicable to thermoforming and blister machines.

Product presence, shape, colour, dimensions, mix-up, package integrity and defectivity controls: these are just few examples of the many controls that Harleblister can do.

100% of products passing under cameras are controlled: to pass the inspection, each blister must match a complete set of acceptance criteria, fully configurable.

Changing the working format is easy: the system include a wizard function that offers an easy way to display complex configuration options, this means that it guides the operator along the phases of format creation, without the need of software programming skills.

The vision system can perform other controls too, such as codes and variable data printed on the product’s lidding foil and PQV on printed artwork. Harleblister controls different products inside the same blister and much more.

The HMI display shows in real-time the results of every product checked, and while 100% of products units are inspected. The vision system manages the rejection of each non-compliant item.

The optimized touch screen display allow an intuitive and straightforward use. In order to grant perfect control for each specific application, material, or machine configuration, harleblister is equipped with an optimal combination of optics and LED light units.

HANDLED PRODUCTS

Oral solid dosage forms, blisters

100% complete inspection

Accurate blister control, down to the finest details

Harleblister performs a wide range of controls. Thanks to multiproduct management, it is also possible to check different products inside the same blister. The printer’s communication management allows the vision system to perform additional PQV and OCV/OCR controls on the blister, such as codes and variable data printing and inspection on the product’s lidding foil (alucode).

Controls on single product (tablet, capsule)

  • Size
  • Colour
  • Shape
  • Integrity (broken tablet, open capsule, presence of fragments or other)

Controls on blister

  • Verification of the correct number of products inside the blister
  • Double products presence in cavity
  • Presence of stray dust or impurities
  • Product Mix up

Controls on blister lidding foil

  • OCV/OCR control for the printed data on the cover material
  • Code control (barcodes, 2D and alphanumerical codes) on the cover material
  • PQV – Print quality verification on the cover material
  • Alucode (lidding material verification)

Customized controls

The system can perform a number of controls with customized parameters, by mean of the programmable measures function. It is a library of image processing applications that can be combined to create specific control with dedicated acceptance conditions as needed. An example? The verification of a text or a logo printed on the tablet.

Flexible and customizable controls

Inspected products and materials

Harleblister can control all solid oral products, always with optimal results:

  • White and coloured tablets
  • Uncoated and coated tablets
  • Monochromatic capsules
  • Bicoloured capsules
  • Softgel capsules

Harleblister performs controls on any type of material:

  • Transparent PVC
  • Opaque PVC
  • Amber PVC
  • Polypropylene
  • PVDC
  • Aluminium/Aluminium

OPERATIVE PRINCIPLES

Designed to boost performances

Harleblister makes use of cameras for the images acquisition and processes them with a proprietary software installed on an industrial PC. The values measured for each object are compared with reference models and, if one of them is outside the tolerance range, the system automatically send a signal to the machine, allowing the rejection of the defective blister.

An accurate inspection is granted, in just milliseconds.

Such rapid elaboration times are possible thanks to Harleblister system’s SIMD instructions developed in-house, and smart proprietary algorithms (designed upon the concepts of spatial and temporal parallelism) programmed to make the most of all the threads available in the latest generation CPUs.

Since threads divide the core of a CPU into many virtual multiple cores, the usage of all of them allow a computer processor to perform multiple tasks at the same time, and faster.

The result is that the algorithms of Harleblister are able to improve theirself software computing power; reducing the images processing times, while performing more controls, and guaranteeuing at the same time the best results in term of inspection accuracy and safety.

Hardware features

The importance of a good hardware

The system is provided with latest genereation industrial computers including a multicore technology and multithreaded processors, in order to take full advantage in terms of elaboration speed and accuracy.

Optics and light units components are specifically designed and assembled for an optimal inspection, and for a perfect integration with the machines mechanical design. With an optimized lighting management, the images acquisition speed is fast and accurate.

The touch-screen displays provided have optimized graphic interface that increases usability and interaction.

PHARMA SPECIFIC SOLUTION

Compliance

The system is specifically designed for the pharmaceutical market, and it is compliant with the industry regulations, with user access regulated by FDA 21 CFR part 11 and annex 11 regulations.

All events are registered by the software in an audit trail file to keep track of all the security-relevant activities.

The continuous Software development follows Gamp 5 regulation, to always improve products quality and consistency.

Integration with machines

The result of a broad experience of vision systems integration

SEA Vision is a pioneer in the development of machine vision systems for blister control. Our expertise in integration is built on decades of experience working alongside machine manufacturers to satisfy the needs of pharmaceutical customers worldwide. Since 1995, over 1700 vision systems have been installed in more than 70 worldwide countries, on blistering machines produced by several manufacturers.

Such experience guarantees efficient machine integration, accurate signal exchange management, and integrated automation and rejection logic.

Harleblister can be integrated on different machines, from entirely automated or semi-automated to modules with a low automation level.

The graphical oscilloscope allows the observation of signal patterns and keeps them under control, facilitating the diagnostical operation.

The entire process is handled efficiently, from the control execution to the rejection of defective products.

A reliable and future-proof solution

Fully integrated with yudoo

Harleblister is natively integrated with Yudoo, the 4.0 pharmaceutical software suite for the full management of automation processes, digital quality, data analysis and for Track&Trace. A digital hub that is everywhere accessible through a secure-access web interface or dedicated devices.

A scalable and modular suite, including tools for automation (centralized management of production, workflows and timesheet), for the digital quality (creation of paperless systems, support systems for line clearance operations), for data analysis (analysis of production data, business intelligence dashboard, condition monitoring and predictive maintenance) and for Track and Trace (complete solutions for Level 3 and 4 of serialization, monitoring of serialization operations).

Yudoo offers multiple advantages such as the possibility to centralize production formats and data, avoiding duplicates and reducing work time. The suite can connect to existing company systems to retrieve updated data exactly from where they are.

A PORTFOLIO OF NATIVELY INTEGRATED SOLUTIONS

One player, one vendor, one solution provider

SEA Vision provides an extensive product portfolio of natively integrated solutions. Vision, traceability and data management solutions for pharmaceutical packaging lines are developed with a common approach to obtain a seamless ecosystem.

Discover our Vision Systems portfolio